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Drug ReportsCAPROMAB PENDETIDE
CAPROMAB PENDETIDE
ProstaScint (capromab pendetide) is an antibody drug conjugate pharmaceutical. Capromab pendetide was first approved as Prostascint on 1996-10-28. It is known to target glutamate carboxypeptidase 2.
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Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Capromab pendetide
Tradename
Proper name
Company
Number
Date
Products
ProstaScintcapromab pendetideAytu BiopharmaN-103608 DISCN1996-10-28
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
V: Various drug classes in atc
— V09: Diagnostic radiopharmaceuticals
— V09I: Tumour detection radiopharmaceuticals
— V09IB: Indium (111in) compounds
— V09IB04: Indium (111in) capromab pendetide
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471—C6143——17
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.0————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCAPROMAB PENDETIDE
INN_
Description
Indium in 111 capromab pendetide is an antibody pharmaceutical. It is currently being investigated in clinical studies.
Classification
Antibody
Drug classmonoclonal antibodies; peptides
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2108800
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDBDO5072GRX (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
FOLH1
FOLH1
Organism
Homo sapiens
Gene name
FOLH1
Gene synonyms
FOLH, NAALAD1, PSM, PSMA
NCBI Gene ID
2346
Protein name
glutamate carboxypeptidase 2
Protein synonyms
Cell growth-inhibiting gene 27 protein, FGCP, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, GCPII, glutamate carboxylase II, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, mGCP, N-acetylated alpha-linked acidic dipeptidase 1, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, PSM, PSMA, Pteroylpoly-gamma-glutamate carboxypeptidase
Uniprot ID
Q9HBA9
Mouse ortholog
Folh1 (53320)
glutamate carboxypeptidase 2 (Q9DCC2)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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